:root{
  --paper:#F5F7F8;      /* cool clinical off-white */
  --panel:#FFFFFF;
  --ink:#16202A;        /* near-black slate */
  --muted:#5C6B78;
  --line:#DCE3E8;
  --teal:#0E7C86;       /* primary — clinical teal */
  --teal-d:#0A5A62;
  --amber:#C77A21;      /* caution / research-only */
  --amber-bg:#FBF1E2;
  --green:#2E7D5B;      /* approved / verified */
  --green-bg:#E7F2EC;
  --red:#B23A34;        /* folklore / danger */
  --red-bg:#F7E7E5;
  --ink-blue:#1B4D7A;
}
*{margin:0;padding:0;box-sizing:border-box}
html{scroll-behavior:smooth}
body{background:var(--paper);color:var(--ink);
  font-family:"Inter","Helvetica Neue",Arial,sans-serif;font-size:17px;line-height:1.6;-webkit-font-smoothing:antialiased}
.wrap{max-width:1120px;margin:0 auto;padding:0 22px}
.narrow{max-width:820px}
a{color:var(--teal);text-decoration:none}
a:hover{text-decoration:underline}
a:focus-visible,button:focus-visible,input:focus-visible,select:focus-visible{outline:2px solid var(--teal);outline-offset:2px}
h1,h2,h3{font-family:"Newsreader","Georgia",serif;font-weight:600;line-height:1.12;letter-spacing:-.01em}
.mono{font-family:"IBM Plex Mono",ui-monospace,monospace}

/* nav */
.topbar{position:sticky;top:0;z-index:50;background:rgba(245,247,248,.9);backdrop-filter:blur(8px);border-bottom:1px solid var(--line)}
.topbar .wrap{display:flex;align-items:center;justify-content:space-between;height:62px;gap:16px}
.brand{display:flex;align-items:center;gap:10px;font-family:"Newsreader",serif;font-weight:600;font-size:20px;color:var(--ink);white-space:nowrap}
.brand .dot{width:11px;height:11px;border-radius:50%;background:var(--teal);box-shadow:0 0 0 4px rgba(14,124,134,.15)}
.brand small{font-family:"IBM Plex Mono",monospace;font-size:11px;color:var(--muted);letter-spacing:.05em;font-weight:400}
.navlinks{display:flex;gap:22px;font-size:15px;font-weight:500}
.navlinks a{color:var(--muted)} .navlinks a:hover,.navlinks a[aria-current]{color:var(--teal);text-decoration:none}
.burger{display:none;flex-direction:column;gap:5px;width:42px;height:38px;justify-content:center;background:none;border:1px solid var(--line);border-radius:8px;cursor:pointer;padding:0 9px}
.burger span{height:2px;background:var(--ink);border-radius:2px;transition:.3s}
.burger[aria-expanded="true"] span:nth-child(1){transform:translateY(7px) rotate(45deg)}
.burger[aria-expanded="true"] span:nth-child(2){opacity:0}
.burger[aria-expanded="true"] span:nth-child(3){transform:translateY(-7px) rotate(-45deg)}
@media(max-width:820px){
  .burger{display:flex}
  .navlinks{position:absolute;top:62px;left:0;right:0;flex-direction:column;gap:0;background:var(--panel);border-bottom:1px solid var(--line);max-height:0;overflow:hidden;transition:max-height .35s ease}
  .navlinks.open{max-height:360px}
  .navlinks a{padding:14px 22px;border-top:1px solid var(--line)}
}

/* disclaimer ribbon */
.ribbon{background:var(--ink);color:#DCE7EA;font-size:13px;text-align:center;padding:8px 22px;font-family:"IBM Plex Mono",monospace;letter-spacing:.02em}
.ribbon b{color:#fff}

/* hero */
.hero{padding:66px 0 40px;border-bottom:1px solid var(--line)}
.eyebrow{font-family:"IBM Plex Mono",monospace;font-size:12.5px;letter-spacing:.18em;text-transform:uppercase;color:var(--teal)}
.hero h1{font-size:clamp(38px,6vw,64px);margin:14px 0 16px;max-width:16ch}
.hero p.lead{font-size:20px;color:var(--muted);max-width:60ch}
.hero .cta{margin-top:28px;display:flex;gap:14px;flex-wrap:wrap}
.btn{display:inline-block;background:var(--teal);color:#fff;font-weight:600;font-size:16px;padding:14px 26px;border-radius:10px;border:0;cursor:pointer;transition:transform .2s,background .2s}
.btn:hover{background:var(--teal-d);text-decoration:none;transform:translateY(-2px)}
.btn.alt{background:transparent;color:var(--teal);border:1.5px solid var(--line)}
.btn.alt:hover{border-color:var(--teal);background:#fff}

/* reveal */
.reveal{opacity:0;transform:translateY(22px);transition:opacity .7s ease,transform .7s cubic-bezier(.2,.7,.2,1)}
.reveal.in{opacity:1;transform:none}
.reveal.d1{transition-delay:.08s}.reveal.d2{transition-delay:.16s}.reveal.d3{transition-delay:.24s}
@media (prefers-reduced-motion:reduce){*{animation:none!important;transition:none!important}.reveal{opacity:1;transform:none}html{scroll-behavior:auto}}

/* section */
section{padding:56px 0}
.shead{max-width:64ch}
.shead .eyebrow{margin-bottom:8px}
.shead h2{font-size:clamp(28px,4vw,40px)}
.shead p{color:var(--muted);margin-top:10px}

/* evidence badges */
.badge{display:inline-flex;align-items:center;gap:7px;font-family:"IBM Plex Mono",monospace;font-size:12px;font-weight:600;letter-spacing:.04em;
  padding:5px 11px;border-radius:999px;border:1px solid;text-transform:uppercase}
.badge::before{content:"";width:8px;height:8px;border-radius:50%;background:currentColor}
.badge.human{color:var(--green);background:var(--green-bg);border-color:#BFE0CE}
.badge.animal{color:var(--amber);background:var(--amber-bg);border-color:#EBD3AC}
.badge.folklore{color:var(--red);background:var(--red-bg);border-color:#E7C3BF}
.badge.approved{color:var(--green);background:var(--green-bg);border-color:#BFE0CE}
.badge.research{color:var(--amber);background:var(--amber-bg);border-color:#EBD3AC}

/* cards grid */
.grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(280px,1fr));gap:20px;margin-top:34px}
.pcard{display:block;background:var(--panel);border:1px solid var(--line);border-radius:14px;padding:22px;transition:transform .25s,box-shadow .25s,border-color .25s}
.pcard:hover{transform:translateY(-4px);box-shadow:0 12px 30px rgba(22,32,42,.09);border-color:#C4D2DA;text-decoration:none}
.pcard .nm{font-family:"Newsreader",serif;font-size:22px;font-weight:600;color:var(--ink)}
.pcard .ab{font-family:"IBM Plex Mono",monospace;font-size:12px;color:var(--muted);margin:2px 0 12px}
.pcard .dz{color:var(--muted);font-size:15px;margin-top:12px}

/* calculator */
.calc{display:grid;grid-template-columns:1fr 1fr;gap:26px;margin-top:34px}
@media(max-width:800px){.calc{grid-template-columns:1fr}}
.panel{background:var(--panel);border:1px solid var(--line);border-radius:16px;padding:26px}
.field{margin-bottom:20px}
.field:last-child{margin-bottom:0}
label{display:block;font-weight:600;font-size:14px;margin-bottom:7px}
label .h{font-weight:400;color:var(--muted);font-family:"IBM Plex Mono",monospace;font-size:12px}
.inrow{display:flex;gap:10px}
input[type=number]{width:100%;background:var(--paper);border:1px solid var(--line);border-radius:10px;color:var(--ink);
  font-family:"IBM Plex Mono",monospace;font-size:20px;padding:13px 14px;-moz-appearance:textfield}
input::-webkit-outer-spin-button,input::-webkit-inner-spin-button{-webkit-appearance:none}
.unit{align-self:center;font-family:"IBM Plex Mono",monospace;color:var(--muted);min-width:46px}
.f-a input{border-left:3px solid var(--teal)}
.f-b input{border-left:3px solid var(--ink-blue)}
.f-c input{border-left:3px solid var(--amber)}
.hintline{font-size:13px;color:var(--muted);margin-top:6px}
.answer{text-align:center;padding:8px 0 4px}
.answer .n{font-family:"IBM Plex Mono",monospace;font-weight:600;font-size:clamp(46px,8vw,72px);color:var(--teal);line-height:1}
.answer .u{color:var(--muted);font-size:15px}
.syringe{width:100%;margin:16px 0}
.readout{font-family:"IBM Plex Mono",monospace;font-size:13.5px;color:var(--muted);line-height:1.8;text-align:center}
.readout b{color:var(--ink)}
.warn{display:none;margin-top:14px;background:var(--amber-bg);border:1px solid #EBD3AC;color:#7c4a10;border-radius:10px;padding:11px 14px;font-size:14px}
.warn.on{display:block}
.warn.danger{background:var(--red-bg);border-color:#E7C3BF;color:#7c211b}
.stats{display:grid;grid-template-columns:repeat(3,1fr);gap:12px;margin-top:22px}
@media(max-width:520px){.stats{grid-template-columns:1fr}}
.stat{border:1px solid var(--line);border-radius:12px;padding:14px 16px;background:var(--panel)}
.stat .k{font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:.08em;text-transform:uppercase;color:var(--muted)}
.stat .v{font-family:"IBM Plex Mono",monospace;font-size:22px;font-weight:600;margin-top:4px}
.stat .v small{font-size:12px;color:var(--muted);font-weight:400}

/* article (dictionary entry) */
.entry-hero{padding:44px 0 26px;border-bottom:1px solid var(--line)}
.entry-hero .row{display:flex;align-items:center;gap:14px;flex-wrap:wrap;margin-bottom:14px}
.entry-hero h1{font-size:clamp(34px,5.5vw,54px)}
.entry-hero .sub{color:var(--muted);font-size:19px;margin-top:10px;max-width:62ch}
.factbox{display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));gap:0;border:1px solid var(--line);border-radius:14px;overflow:hidden;margin:30px 0}
.factbox div{padding:16px 18px;border-right:1px solid var(--line);border-bottom:1px solid var(--line)}
.factbox .k{font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:.06em;text-transform:uppercase;color:var(--muted)}
.factbox .v{font-weight:600;margin-top:4px;font-size:15px}
.prose{max-width:70ch}
.prose h2{font-size:26px;margin:38px 0 12px}
.prose h3{font-size:20px;margin:26px 0 8px}
.prose p{margin-bottom:16px}
.prose ul{margin:0 0 16px 22px}
.prose li{margin-bottom:7px}
.callout{border-left:3px solid var(--teal);background:var(--panel);border-radius:0 12px 12px 0;padding:16px 20px;margin:22px 0}
.callout.amber{border-color:var(--amber);background:var(--amber-bg)}
.callout.red{border-color:var(--red);background:var(--red-bg)}
.callout .lbl{font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:.08em;text-transform:uppercase;color:var(--muted);margin-bottom:6px}
.srcs{margin-top:40px;border-top:1px solid var(--line);padding-top:20px}
.srcs h3{font-size:16px;font-family:"IBM Plex Mono",monospace;text-transform:uppercase;letter-spacing:.06em;color:var(--muted);margin-bottom:12px}
.srcs ol{margin-left:20px;font-size:14px;color:var(--muted)}
.srcs li{margin-bottom:8px}

/* pager */
.pager{display:flex;justify-content:space-between;gap:14px;margin:44px 0 0}
.pager a{flex:1;background:var(--panel);border:1px solid var(--line);border-radius:12px;padding:14px 18px}
.pager a:hover{border-color:var(--teal);text-decoration:none}
.pager .l{font-family:"IBM Plex Mono",monospace;font-size:11px;color:var(--muted);letter-spacing:.08em}
.pager .t{font-family:"Newsreader",serif;font-size:18px;font-weight:600;color:var(--ink)}
.pager .nxt{text-align:right}

/* footer */
footer{background:var(--ink);color:#B7C4CD;padding:44px 0 40px;margin-top:60px}
footer a{color:#8FD3D9}
footer .cols{display:grid;grid-template-columns:2fr 1fr 1fr;gap:30px}
@media(max-width:700px){footer .cols{grid-template-columns:1fr}}
footer h4{color:#fff;font-family:"IBM Plex Mono",monospace;font-size:12px;letter-spacing:.08em;text-transform:uppercase;margin-bottom:12px}
footer ul{list-style:none}
footer li{margin-bottom:8px;font-size:15px}
footer .legal{margin-top:30px;padding-top:20px;border-top:1px solid #2a3742;font-size:12.5px;line-height:1.6;color:#8496A2;max-width:80ch}

/* search */
.searchwrap{position:relative;margin-top:26px;max-width:620px}
.searchwrap .si{position:absolute;left:16px;top:50%;transform:translateY(-50%);color:var(--muted)}
#psearch{width:100%;font-size:18px;padding:15px 16px 15px 46px;border:1.5px solid var(--line);border-radius:12px;background:var(--panel);color:var(--ink);font-family:inherit}
#psearch:focus{border-color:var(--teal);outline:none;box-shadow:0 0 0 3px rgba(14,124,134,.15)}
.searchmeta{margin-top:10px;font-family:"IBM Plex Mono",monospace;font-size:13px;color:var(--muted);min-height:18px}

/* evidence tiers */
.tiers{display:flex;flex-direction:column;gap:14px;margin-top:20px}
.tierrow{display:grid;grid-template-columns:170px 1fr;gap:16px;align-items:center;background:var(--panel);border:1px solid var(--line);border-radius:12px;padding:16px 18px}
.tierrow p{margin:0;color:var(--muted)}
@media(max-width:560px){.tierrow{grid-template-columns:1fr;gap:8px}}

/* ===== hero ambient molecular chain ===== */
.hero{position:relative;overflow:hidden}
.molecule{position:absolute;inset:0;z-index:0;pointer-events:none;opacity:.5}
.molecule line{stroke:var(--teal);stroke-width:1.2;opacity:.25}
.molecule circle{fill:var(--teal);opacity:.55}
.molecule .n2{fill:var(--ink-blue);opacity:.4}
.hero .wrap{position:relative;z-index:1}
@keyframes floatnode{0%,100%{transform:translateY(0)}50%{transform:translateY(-10px)}}
.molecule .float{transform-box:fill-box;transform-origin:center;animation:floatnode 6s ease-in-out infinite}
@keyframes dashdraw{to{stroke-dashoffset:0}}
.molecule .draw{stroke-dasharray:var(--len);stroke-dashoffset:var(--len);animation:dashdraw 1.6s ease forwards}

/* ===== count-up + syringe intro ===== */
@keyframes fillgrow{from{width:0}}
.answer .n{transition:color .3s}

/* ===== evidence meter (compound + dictionary) ===== */
.emeter{margin:6px 0 2px;height:8px;border-radius:6px;background:#E7EDF0;overflow:hidden;position:relative}
.emeter i{display:block;height:100%;width:0;border-radius:6px;transition:width 1.1s cubic-bezier(.3,.8,.3,1)}
.emeter.approved i,.emeter.human i{background:linear-gradient(90deg,#2E7D5B,#57b489)}
.emeter.trial i{background:linear-gradient(90deg,#C77A21,#e0a24e)}
.emeter.animal i{background:linear-gradient(90deg,#C77A21,#d9954a)}
.emeter.folklore i{background:linear-gradient(90deg,#B23A34,#d76a63)}
.emeter-row{display:flex;align-items:center;gap:12px;margin:20px 0}
.emeter-row .lab{font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:.06em;text-transform:uppercase;color:var(--muted);white-space:nowrap;min-width:118px}
.emeter-row .em-wrap{flex:1}
.emeter-row .em-val{font-family:"IBM Plex Mono",monospace;font-size:12px;color:var(--muted);min-width:96px;text-align:right}

/* card hover sheen */
.pcard{position:relative;overflow:hidden}
.pcard::after{content:"";position:absolute;top:0;left:-60%;width:40%;height:100%;
  background:linear-gradient(100deg,transparent,rgba(14,124,134,.07),transparent);transform:skewX(-18deg);transition:left .6s ease}
.pcard:hover::after{left:130%}

/* animated dot pulse in brand */
.brand .dot{position:relative}
.brand .dot::after{content:"";position:absolute;inset:0;border-radius:50%;background:var(--teal);animation:pulse 2.4s ease-out infinite}
@keyframes pulse{0%{transform:scale(1);opacity:.5}70%,100%{transform:scale(2.6);opacity:0}}

@media (prefers-reduced-motion:reduce){
  .molecule .float,.molecule .draw,.brand .dot::after{animation:none}
  .molecule .draw{stroke-dashoffset:0}
  .emeter i{transition:none}
  .pcard::after{display:none}
}